MODULO 1 |
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Capitolo |
1 |
Venturing through transcriptional and epigenetic lands of adrenocortical tumors |
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Capitolo 2 |
DNA-based markers as a window on intratumor heterogeneity |
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Capitolo 3 |
Cellular senescence in adrenal homeostasis and cancer |
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Capitolo 4 |
Liquid biopsy in the assessment of adrenocortical carcinoma heterogeneity: where are we now? |
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MODULO 2 |
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Capitolo 1 |
PRC2 stabilizes a differentiated cell state required for sustained proliferation in ACC |
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Capitolo 2 |
Combined inactivation of ZNRF3 and TP53 alter the immune microenvironment and favor ACC development |
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Capitolo 3 |
Adrenocortical carcinoma xenograft in zebrafish embryos as a model to study in vivo cytotoxicity of molecular target agents |
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Capitolo 4 |
How to treat ACC by targeting lipid metabolism and ferroptosis |
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Capitolo 5 |
Targeting cytoskeleton dynamics against metastatic dissemination in ACC |
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Capitolo 6 |
Keynote lecture |
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Capitolo 7 |
Proffered papers on preclinical studies in ACC |
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MODULO 3 |
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Capitolo 1 |
Laparoscopic surgery for all, for some, or for none? |
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Capitolo 2 |
Why R0 resection is not attained in all patients? |
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Capitolo 3 |
Surgery in metastatic adrenocortical carcinoma: when and why? |
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Capitolo 4 |
Hyperthermic intraperitoneal chemotherapy and conversion surgery: rationale and results |
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MODULO 4 |
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Capitolo 1 |
How the Adiuvo trial may change clinical practice |
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Capitolo 2 |
Predictive factors of adjuvant mitotane therapy |
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Capitolo 3 |
Adjuvant chemotherapy: is it worth a try? |
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Capitolo 4 |
Adjuvant radiotherapy: new life in an old concept |
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Capitolo 5 |
Keynote lecture: |
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Capitolo 6 |
Proffered papers on preclinical studies in ACC |
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MODULO 5 |
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Capitolo 1 |
Glucocorticoids, microenvironment and potential therapeutic implication |
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Capitolo 2 |
How bad is cortisol excess for patients with adrenal tumors? |
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Capitolo 3 |
Osilodrostat: a new player in the field |
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Capitolo 4 |
Detection and management of mitotane induced hypoadrenalism |
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MODULO 6 |
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Capitolo 1 |
Prognostic factors and their impact on practice |
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Capitolo 2 |
What is oligometastatic ACC? And how to treat it? |
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Capitolo 3 |
New markers and end-points to assess tumor response |
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Capitolo 4 |
Management of advanced adrenocortical cancer in children |
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MODULO 7 |
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Capitolo 1 |
How to exploit preclinical models in the search of new drugs |
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Capitolo 2 |
Next-generation molecular target therapies for adrenocortical carcinoma |
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Capitolo 3 |
Is immunotherapy a game changer? |
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MODULO 8 |
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Capitolo 1 |
Do we know all on unwanted effects of mitotane? |
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Capitolo 2 |
A patient journey in the disease |
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Capitolo 3 |
Role of patient reported outcomes |
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Capitolo 4 |
Emesis management and supportive care in advanced ACC |
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Capitolo 5 |
Keynote lecture |
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